Maarten van der Doelen

Chapter 4

Timepoint T1 versus T0

Timepoint T2 versus T0

Global health status

Global health status

Total cohort

Total cohort

Subgroup 6 injections

Subgroup 6 injections

Subgroup 4-5 injections

Subgroup 4-5 injections

Subgroup 1-3 injections

-50 -40 -30 -20 -10

0 10 20 30

-50 -40 -30 -20 -10

0 10 20 30

Mean difference (95% CI) from baseline

Mean difference (95% CI) from baseline

Physical functioning

Physical functioning

Total cohort

Total cohort

Subgroup 6 injections

Subgroup 6 injections

Subgroup 4-5 injections

Subgroup 4-5 injections

Subgroup 1-3 injections

-50 -40 -30 -20 -10

0 10 20 30

-50 -40 -30 -20 -10

0 10 20 30

Mean difference (95% CI) from baseline

Mean difference (95% CI) from baseline

Role functioning

Role functioning

Total cohort

Total cohort

Subgroup 6 injections

Subgroup 6 injections

Subgroup 4-5 injections

Subgroup 4-5 injections

Subgroup 1-3 injections

-50 -40 -30 -20 -10

0 10 20 30

-50 -40 -30 -20 -10

0 10 20 30

Mean difference (95% CI) from baseline

Mean difference (95% CI) from baseline

Emotional functioning

Emotional functioning

Total cohort

Total cohort

Subgroup 6 injections

Subgroup 6 injections

Subgroup 4-5 injections

Subgroup 4-5 injections

Subgroup 1-3 injections

-50 -40 -30 -20 -10

0 10 20 30

-50 -40 -30 -20 -10

0 10 20 30

Mean difference (95% CI) from baseline

Mean difference (95% CI) from baseline

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