Maarten van der Doelen

Chapter 4

Fatigue

Nausea and vomiting

Pain

1-3

4-5

6 injections

1-3

4-5

6 injections

1-3

4-5

6 injections

80

80

80

60

60

60

40

40

40

Mean score

Mean score

Mean score

20

20

20

0

0

0

T0

T1

T2

T0

T1

T2

T0

T1

T2

Time point

Time point

Time point

Dyspnoea

Insomnia

Appetite loss

1-3

4-5

6 injections

1-3

4-5

6 injections

1-3

4-5

6 injections

80

80

80

60

60

60

40

40

40

Mean score

Mean score

Mean score

20

20

20

0

0

0

T0

T1

T2

T0

T1

T2

T0

T1

T2

Time point

Time point

Time point

Supplementary figure 6. Course of cancer-specific health-related quality of life (EORTC QLQ-C30 symptom scales) over time in patients treated with radium-223 for metastatic castration-resistant prostate cancer. Bars indicate mean scores with 95% confidence intervals.

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