Maarten van der Doelen

Chapter 4

HADS - Anxiety score

HADS - Depression score

1-3

6 injections

1-3

6 injections

4-5

4-5

15

15

10

10

5

5

Mean score

Mean score

0

0

T0

T1

T2

T0

T1

T2

Time point

Time point

HADS - Total score

CIS - Fatigue

1-3

6 injections

1-3

6 injections

4-5

4-5

60

30

50

20

40

10

Mean score

30 Mean score

0

20

T0

T1

T2

T0

T1

T2

Time point

Time point

Supplementary figure 8. Course of psychological distress and fatigue (HADS and CIS-Fatigue) over time in patients treated with radium-223 for metastatic castration-resistant prostate cancer. The dotted line indicates cut-off scores for the HADS total score and CIS-Fatigue.

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