Maarten van der Doelen

Chapter 2

Supplementary table 3. Outcomes of EORTC QLQ-C30 and EORTC QLQ-BM22 questionnaires.

Follow-up 12 months (n=5)

Follow-up 18 months (n=3)

Baseline (n=7)

End of therapy (n=7)

EORTC QLQ-C30 questionnaire Functional scales a Physical

67 [53-80]

73 [60-100]

87 [30-93]

67 NA

Role

33 [33-67]

50 [33-100]

83 [8-100]

67 NA

Emotional

75 [42-75]

75 [67-100]

83 [67-92]

83 NA

Cognitive

100 [50-100]

100 [67-100]

83 [58-100]

100 NA

Social

83 [50-100]

67 [33-100]

83 [33-100]

50 NA

Symptom scales and items b Fatigue

56 [33-67]

33 [22-78]

22 [17-83]

56 NA

Nausea and vomiting

17 [0-50]

0 [0-17]

0 [0-33]

0 NA

Pain

50 [50-67]

17 [0-33]

17 [0-92]

17 NA

Dyspnoea

67 [33-67]

33 [0-33]

0 [0-50]

33 NA

Insomnia

33 [33-100]

33 [0-100]

0 [0-67]

33 NA

Appetite loss

33 [0-100]

0 [0-67]

0 [0-50]

33 NA

Constipation

0 [0-67]

0 [0-67]

33 [0-67]

0 NA

Diarrhea

0 [0-33]

0 [0-0]

0 [0-0]

33 NA

Financial difficulties

0 [0-0]

0 [0-0]

0 [0-50]

0 NA

58 [50-83]

75 [33-83]

75 [42-88]

58 NA

Global health status c

EORTC QLQ-BM22 questionnaire Symptom scales Painful sites b

27 [20-40]

7 [0-27]

7 [0-27]

7 NA

Pain characteristics b

22 [22-33]

11 [0-22]

22 [0-50]

11 NA

Functional scales

75 [50-88]

96 [83-100]

96 [65-98]

83 NA

Functional interference a

Psychosocial aspects b 67 NA Data are presented as median scores [IQR]. EORTC = European Organization for Research and Treatment of Cancer; NA = not applicable; QLQ-BM22 = Quality of Life Questionnaire-Bone Metastases 22; QLQ-C30 = Quality of Life Questionnaire-Core 30. a Higher scores indicate better functioning. b Higher scores indicate worse symptoms/aspects. c Higher scores indicate higher quality of life. 56 [50-67] 50 [39-61] 72 [50-83]

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