Roel Bogie

Thermal ablation of mucosal defect margins to prevent local recurrence of large colorectal polyps: A systematic review and meta-analysis

Recurrence risk

Risk

Author and year STSC Park (2019)* Klein (2019) Kandel (2019) Shahidi (2020) Shahidi (2021)

RD [95% CI]

IG CG

0.05 0.60 0.05 0.21 0.12 0.30 0.04 0.19 0.01 0.17

-0.55 [-0.98 , -0.12] -0.16 [-0.23 , -0.09] -0.18 [-0.32 , -0.04] -0.16 [-0.22 , -0.09] -0.16 [-0.20 , -0.13]

Estimated rate:

-0.16 [-0.19 , -0.14]

APC Brooker (2002)*

0.10 0.64

-0,54 [-0.88 , -0.20] 0.02 [-0.32 , 0.35]

6

Albuquerque (2013) 0.20 0.18

Estimated rate:

-0.26 [-0.80 , 0.28]

Total:

-0.17 [-0.22 , -0.12]

I 2 = 33,58%

1 0 Risk difference of recurrence -0.5 -1 Figure 6.2: Pooled data of included studies. | IG = intervention group; CG = control group; RD = risk difference; STSC = snare tip soft coagulation; APC = argon plasma coagulation. * Not all included lesions in this study are ≥20mm in size. 0.5

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