Roel Bogie

Chapter 4

Time trends in LST resection

Surgery En-bloc resection Piecemeal resection / no resection Total number of LSTs

70

60

50

40

30

50.0%

20 Number of LSTs

29.6%

10

16.7%

11.7%

0

Year 1

Year 2

Year 3

Year 4

LSTs resected by year

Figure 4.2: Time trends in resection of LSTs after training at our institution.

Table 4.3: Synchronous findings in patients with ≥1 LST at index colonoscopy with patients with ≥1 large polypoid colorectal neoplasm (LP-CRN) at index colonoscopy. | CRN: colorectal neoplasm, HGD: high grade dysplasia, SMI: submucosal invasion, yrs: years.

Clinical features

Patients with ≥1 neoplastic LST (n=151)

Patients with ≥1 LP-CRN (no LSTs) (n=566)

P value

Mean age, yrs (SD)

67.6 (10.7)

67.9 (11.5) 313 (55.3) 4.90 (1.92) 3.55 (1.70) 1.51 (0.79) 2.34 (2.38) 0.09 (0.37)

0.800 0.942 0.189 0.881

Male (%)

83 (55.0)

Mean FU time, yrs (SD)

5.11 (1.76)

Mean time till last FU scopy, yrs (SD) 3.59 (1.65)

Mean number of FU scopies (SD)

2.15 (1.36)

<0.001 <0.001 <0.001

Mean number of CRNs at index (SD) 3.34 (2.61)

Mean number of non-polypoid CRNs at index (SD) Mean number of CRNs with HGD/ SMI at index (SD) Mean number of adenomas at index (SD)

1.52 (1.00)

1.96 (1.56)

1.51 (1.17)

0.001

2.71 (2.33)

1.90 (2.04)

<0.001

Mean number of CRCs at index (SD) 0.17 (0.42)

0.28 (0.47) 0.37 (0.88)

0.003 0.221

Mean number of serrated neoplasms at index (SD)

0.50 (1.14)

80