Maarten van der Doelen

Chapter 4

0.208

0.466

0.085

0.077

0.866

0.077

0.408

0.064

0.006

0.003

0.016

0.011

None

None

Small

Moderate Small

Moderate Small

Small

Moderate

Moderate

Moderate

Moderate

-5.4

-3.4

-9.6

-5.3

+0.6

+9.6

-15.8

-12.2

-13.3

Mean difference CRC P value +14.2 +13.2 +12.5

-

-

-

-

(23.1)

(23.1)

(24.6)

(24.6)

(25.8)

(25.8)

(24.3)

(24.3)

-

-

-

-

43.1

43.1

35.8

35.8

60.7

60.7

34.7

34.7

Time point T2

Mean (SD) score

(18.7) -

(19.6) -

(21.4) -

(20.2) -

(18.9)

(21.3)

(21.5)

(18.1)

52.9 -

23.5 -

71.0 -

21.2 -

55.2

26.3

70.3

22.2

Time point T1

Mean (SD) score

(17.5) -

(20.8) -

(22.4) -

(19.7) -

(17.1)

(20.1)

(21.5)

(24.0)

21.7 -

74.0 -

58.8 -

21.5 -

Mean (SD) score 22.9

74.4

58.3

26.5

Time point T0

time points N 21

16

16

21

16

16

21

16

16

21

16

16

BM-22 symptom scales b Painful sites T0-T1 T0-T2 T1-T2

BM-22 functional scales a Functional interference T0-T1 T0-T2 T1-T2

Psychosocial aspects T0-T1 T0-T2 T1-T2

Pain characteristics T0-T1 T0-T2 T1-T2

Comparison

Supplementary table 4A. Continued.

CRC, Clinically relevant change, defined as small (5-10 points), moderate (10-20 points), or large (>20 points).

Mean health-related quality of life scores range from 0 to 100. a Functional and global scales: high scores indicate high level of functioning. b Symptom scales: high scores indicate high symptom burden.

126